I had to disable statistic relays to bring down the CPU usage to an acceptable level for single core proc. I originally tested on a single core dedicated box, however resource usage was high and the system was unstable. I was unable to install gecko or msxml3 (as the instructions on winehq state are necessary), However I was still able to install and run SAM without them. I have not tested everything, but I have had no show stopping issues for anything I've tested. All the essential features: Playback, Encoding/Streaming, Relay Statistics, DSPs, FX, Playlist, Mysql connections (remote and local), PAL Script Execution, Playlist Rotation, Remote requests.